ABSTRACT
Background: Red reflex screening is the primary but unheeded test for the detection of vision- and life-threatening eye conditions.
Aims: To evaluate the red reflex of newborns, percentage of ocular diseases resulting in red reflex abnormality, and their relation with consanguinity in Southeast Turkey.
Methods: Newborns [n = 1358] were examined with pencil light and direct ophthalmoscopy.
Results: Eight hundred of these newborns were hospitalized in a rooming-in unit. [RIU] and 558 were in the neonatal intensive care service [NICS]. In the RIU there were 7 [0.88%] newborns with abnormal red reflex and in the NICS there were 14 [2.51%]. Sensitivity of pencil light examination was 71.4%. Studies from the Middle East have shown potential recessive genetic causes of common paediatric ocular conditions. In our study, consanguineous marriage was found to have a significant association with red reflex abnormality [P = 0.017].
Conclusions: Red reflex screening test is important in the early diagnosis of vision- and life-threatening eye disorders in Southeast Turkey where consanguinity is common
Subject(s)
Humans , Infant, Newborn , Consanguinity , Intensive Care, Neonatal , Infant, Newborn , Prospective Studies , Cataract/congenital , HospitalizationABSTRACT
PURPOSE: The purpose of this study is to evaluate the prognostic role of preoperative neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) and the need for para-aortic lymphadectomy in patients with primary fallopian tube carcinoma (PFTC). MATERIALS AND METHODS: Ninety-one patients with a diagnosis of PFTC were identified through the gynecologic oncology service database of six academic centers. Clinicopathological, surgical, and complete blood count data were collected. RESULTS: In univariate analysis, advanced stage, suboptimal surgery, and NLR > 2.7 were significant prognostic factors for progression-free survival, whereas in multivariate analysis, only advanced stage and suboptimal surgery were significant. In addition, in univariate analysis, cancer antigen 125 > or = 35 U/mL, ascites, advanced stage, suboptimal surgery, NLR > 2.7, PLR > 233.3, platelet count > or =400,000 cells/mm3, staging type, and histological subtype were significant prognostic factors for overall survival (OS); however, in multivariate analysis, only advanced stage, suboptimal surgery, NLR > 2.7, and staging type were significant. Inclusion of pelvic and para-aortic lymphadenectomy in surgery showed significant association with longer OS, with a mean and median OS of 42.0 months and 35.5 months (range, 22 to 78 months), respectively, vs. 33.5 months and 27.5 months (range, 14 to 76 months), respectively, for patients who underwent surgery without para-aortic lymphadenectomy (hazard ratio, 3.1; 95% confidence interval, 1.4 to 5.7; p=0.002). CONCLUSION: NLR (in both univariate and multivariate analysis) and PLR (only in univariate analysis) were prognostic factors in PFTC. NLR and PLR are inexpensive and easy tests to perform. In addition, patients with PFTC who underwent bilateral pelvic and para-aortic lymphadenectomy had longer OS.
Subject(s)
Female , Humans , Ascites , Blood Cell Count , Blood Platelets , Diagnosis , Disease-Free Survival , Fallopian Tubes , Lymph Node Excision , Lymphocytes , Multivariate Analysis , Neutrophils , Platelet CountABSTRACT
To evaluate the 2-year outcomes of phacoemulsification combined with primary posterior curvilinear capsulorhexis [PPCC] in adults. In this retrospective case series, 93 eyes of 91 patients with bilateral age-related cataract who underwent phacoemulsification combined with PPCC were evaluated. The study included cases due to postoperative residual posterior capsule opacification despite careful polishing. Data were evaluated on preoperative and postoperative best corrected visual acuity [CDVA] [Snellen acuity], slit-lamp biomicroscopy and intraocular pressure [IOP] measurement. Perioperative and postoperative complications were also recorded. The mean follow-up was 24.9 +/- 13.5 months [range, 12-53 months]. At the last visit, 87.1% of the eyes had CDVA>/=20/40 and 58% had>/=20/25. Posterior capsular opacification [PCO] occurred in 2 [2.2%] of patients. No serious complications such as retinal detachment and endophthalmitis were observed during follow-up. Cataract surgery combined with PPCC is a safe procedure with a low rate of complications over the long term. This procedure reduced the necessity of Nd:YAG laser capsulotomy in adults with postoperative residual posterior capsule opacification despite careful polishing
ABSTRACT
Up to 5-10% of Brucellosis cases manifest with neurobrucellosis and course with various forms such as meningocephalitis, cerebellitis, acute meningitis, myelopathy, radiculopathy neuropsychiatric syndromes and cranial neuropathy. Brucella toxin damages the inner ear and leads to sensorineural hearing loss. We aim to report seven patients who were diagnosed as neurobrucellosis accompanying with hearing loss problem and were hospitalized to Infectious Diseases Department between 2005 and 2010. Long term fever, headache, hearing loss, walking disability were the predominant symptoms, Bilateral sensorineural hearing loss was the most frequent finding. And the other findings were also dysarthria, ataxia walking and increased deep tendon reflexes. Common symptoms were long term fever [100%], headache [71.4%], chills [57%], vomiting and exhaustion [29%]. Neurologic findings such as walking instability [four patients], paraplegia [two patients] and hearing disturbances [seven patients] were recognized. Rifampicin, doxycycline and trimethoprim/ sulfamethaxazole agents were administered to our patients and the duration of treatment should be decided depending upon individual cases [4-12 months]. Hearing thresholds were restored after treatment in five patients. Only two patients' hearing loss were partially improved after therapy. Neurobrucellosis should be considered in long term fever accompanying the unexplained neurological symptoms such as hearing loss. In neurobrucellosis patient should be tested in hearing thresholds